FcRn 抗体 (AA 24-215)
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- 抗原 See all FcRn 抗体
- FcRn (IgG receptor FcRn (FcRn))
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抗原表位
- AA 24-215
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FcRn antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
- 克隆位点
- FCGRT-2932
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product FcRn Primary Antibody
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anti-IgG receptor FcRn (FcRn) antibody
FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-365) antibodyFcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-215) antibodyFcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 25-300) antibodyFcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) antibodyFcRn 适用: 人, 小鼠 ELISA, IF, FACS, cELISA 宿主: 小鼠 Monoclonal DVN24 unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: THP1 or HepG2 cells. Cerebellum or Testis.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FcRn (IgG receptor FcRn (FcRn))
- 别名
- FCGRT (FcRn 产品)
- 别名
- FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
- 背景
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Fc fragment of IgG, receptor transporter, alpha, FCGRT, FCRN, alpha chain, IgG Fc fragment receptor transporter alpha chain, IgG Gc receptor, IgG receptor FcRn large subunit p51, Immunoglobulin receptor, intestinal, heavy chain, Neonatal Fc receptor,FCGRT / FcRn (IgG Transporter)
Cellular localisation: Cell Surface and Cytoplasmic - 分子量
- 46kDa
- 基因ID
- 2217, 111903
- UniProt
- P55899
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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