FCGR3A 抗体
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- 抗原 See all FCGR3A 抗体
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR3A antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 特异性
- It recognizes CD16 (FcgammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. Two similar genes represent CD16, CD16A (FcgammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (FcgammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Human CD16 protein
- 克隆位点
- ICO-116
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCGR3A Primary Antibody
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anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 49-184) antibody
FCGR3A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (C-Term) antibodyFCGR3A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-254) antibodyFCGR3A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 26-108) antibodyFCGR3A 适用: 人 WB, ELISA, ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 5-241) antibodyFCGR3A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) antibodyFCGR3A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 1-290) antibodyFCGR3A 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-254) antibodyFCGR3A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 150-250) antibodyFCGR3A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) antibodyFCGR3A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: K-562 or U-937 cells. Lymph nodes and tonsils.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- 别名
- FCGR3A (FCGR3A 产品)
- 别名
- CD16 antibody, CD16A antibody, FCG3 antibody, FCGR3 antibody, FCGRIII antibody, FCR-10 antibody, FCRIII antibody, FCRIIIA antibody, IGFR3 antibody, Fcgr4 antibody, Fc fragment of IgG receptor IIIa antibody, FCGR3A antibody, Fcgr3a antibody
- 背景
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FcRIIIa; FCR-10; FcRIII; FCGRIII; FcR-10; Fc fragment of IgG, low affinity IIIa, receptor for (CD16); neutrophil-specific antigen NA; CD16a; low affinity immunoglobulin gamma Fc region receptor III-A; Fc-gamma RIIIa; immunoglobulin G Fc receptor III; Fc-gamma RIII-alpha; Fc-gamma receptor IIIb (CD16); CD16a antigen; Fc-gamma receptor III-2 (CD16); FCGR3; Fc gamma receptor III-A; FCG3; low affinity III, receptor for (CD16); Fc-gamma RIII; IGFR3FcgammaRIIIA; CD16FCRIIIA; FCRIII; Fc fragment of IgG, low affinity IIIa, receptor (CD16a),CD16 / FcγReceptor III
Cellular localisation: Cell Surface - 分子量
- 50-80kDa
- 基因ID
- 2214, 372679
- UniProt
- P08637
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