FCGR2A 抗体
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- 抗原 See all FCGR2A 抗体
- FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR2A antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- This MAb binds most strongly to the IIa isoforms of CD32 (FcRII), a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human FCGR2A protein
- 克隆位点
- FCGR2A-479
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product FCGR2A Primary Antibody
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anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibody
FCGR2A 适用: 人 WB, IF, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 9C6 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人, 猴 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 20D1 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 241-317) antibodyFCGR2A 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibodyFCGR2A 适用: 人 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人 WB, IF, IHC, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal 6H7 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 34-316) antibodyFCGR2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 46-150) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E8 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 1-316) antibodyFCGR2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 3B6 unconjugated Recombinant Antibody
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- 应用备注
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Known_Application: Functional Studies (Order Ab without BSA & Azide), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: K-562 cells. Lymph node, tonsil and placenta.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
- 别名
- FCGR2A (FCGR2A 产品)
- 别名
- CD32 antibody, CD32A antibody, CDw32 antibody, FCG2 antibody, FCGR2 antibody, FCGR2A1 antibody, FcGR antibody, IGFR2 antibody, CD32a antibody, Fc fragment of IgG receptor IIa antibody, FCGR2A antibody
- 背景
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CD32A, Fc fragment of IgG low affinity IIa receptor, Fc gamma RIIa, FCGR2A, FcgRII, IGFR2, IgG Fc receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-a, Ly-17, Ly-m20, LyM-1, Lymphocyte antigen 17,CD32 (Fc Gamma RIIa)
Cellular localisation: Cell Surface - 分子量
- 40kDa
- 基因ID
- 2212, 352642
- UniProt
- P12318
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