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CYP1A1/2 抗体

CYP1A1/2 适用: 大鼠 WB, IF, IHC (f) 宿主: 小鼠 Monoclonal MC1 unconjugated
产品编号 ABIN6937070
发货至: 中国
  • 抗原 See all CYP1A1/2 抗体
    CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))
    适用
    • 18
    • 17
    • 16
    • 4
    • 2
    • 2
    • 1
    大鼠
    宿主
    • 16
    • 2
    小鼠
    克隆类型
    • 16
    • 2
    单克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1A1/2 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies, the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.
    交叉反应 (详细)
    Human. Mouse. Rat. Primate.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    3-methylcholanthrene induced rat cytochrome P450 protein.
    克隆位点
    MC1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CYP1A1/2 Primary Antibody
  • 应用备注

    Known_Application: Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Liver or Cardiac muscle.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))
    别名
    CYP1A1 / CYP1A2 (CYP1A1/2 产品)
    别名
    CP12 antibody, Cyp1a1 antibody, P450-3 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, Cyp1a2 antibody
    背景
    Aryl hydrocarbon hydroxylase, CP11, CP12, CYP1A1, CYP1A2, CYPIA1, CYPIA2, Cytochrome P450 family 1 subfamily A polypeptide 1, Cytochrome P450 family 1 subfamily A polypeptide 2, P1 450, P3 450, P450 form 4, P450 form 6, P450 P1, P450 P3,Cytochrome P450 1A1/1A2
    Cellular localisation: Cytoplasmic
    分子量
    58kDa
    基因ID
    1543, 1544, 437060
    UniProt
    P04798, P05177
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