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Recombinant G-CSF 抗体

This anti-G-CSF antibody is a 兔 单克隆 antibody detecting G-CSF in IHC 和 IHC (f). Suitable for 人.
产品编号 ABIN6937035
发货至: 中国

Quick Overview for Recombinant G-CSF 抗体 (ABIN6937035)

抗原

See all G-CSF (CSF3) 抗体
G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This G-CSF antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

CSF3-3166R
  • 特异性

    This MAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF s, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF s share 73 % sequence identity at the amino acid level.

    交叉反应 (详细)

    Human. Macaque Monkey.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human CSF3 protein

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Tonsil or lymph node (IHC).

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

    别名

    CSF3

    背景

    Pluripoietin, Filgrastim, Lenograstim, CSF3OS, G-CSF, chromosome 17 open reading frame 33 (C17orf33), colony stimulating factor 3 (granulocyte),Granulocyte-Colony Stimulating Factor (G-CSF)
    Cellular localisation: Cytoplasmic

    分子量

    19kDa

    基因ID

    1440, 2233

    UniProt

    P09919

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
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