CDC34 抗体
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- 抗原 See all CDC34 抗体
- CDC34 (Cell Division Cycle 34 (CDC34))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CDC34 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human full-length CDC34 protein
- 克隆位点
- CPTC-CDC34-2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CDC34 Primary Antibody
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anti-Cell Division Cycle 34 (CDC34) (Internal Region) antibody
CDC34 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-CDC34-2 unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (AA 1-236) antibodyCDC34 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (AA 1-236) antibodyCDC34 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (C-Term) antibodyCDC34 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293, K562, Jurkat cell lysates. Human small intestine.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- CDC34 (Cell Division Cycle 34 (CDC34))
- 别名
- CDC34 (CDC34 产品)
- 别名
- E2-CDC34 antibody, UBC3 antibody, UBCH3 antibody, UBE2R1 antibody, AI327276 antibody, e2-cdc34 antibody, ubc3 antibody, ube2r1 antibody, CDC34 antibody, DNA6 antibody, Ube2r2 antibody, zgc:55452 antibody, fb34h09 antibody, wu:fb34h09 antibody, wu:fe17e09 antibody, zgc:91847 antibody, cell division cycle 34 antibody, cell division cycle 34 L homeolog antibody, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 antibody, SCF E2 ubiquitin-protein ligase catalytic subunit antibody, cell division cycle 34 homolog (S. cerevisiae) a antibody, cell division cycle 34 homolog (S. cerevisiae) b antibody, CDC34 antibody, Cdc34 antibody, cdc34.L antibody, cdc34 antibody, cdc34a antibody, cdc34b antibody
- 背景
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Cdc34, cell division cycle 34, UBC3, UBCH3, UBE2R1, Ubiquitin carrier protein, Ubiquitin conjugating enzyme E2 32 kDa complementing, Ubiquitin protein ligase R1, Ubiquitin conjugating enzyme E2-CDC34,Cell Division Cycle 34 homolog
Cellular localisation: Nucleus. Cytoplasm. - 分子量
- 34kDa
- 基因ID
- 997, 514997
- UniProt
- P49427
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