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BCL2L1 抗体 (AA 1-135)

This anti-BCL2L1 antibody is a 小鼠 单克隆 antibody detecting BCL2L1 in IHC (f). Suitable for 人.
产品编号 ABIN6936491
发货至: 中国

Quick Overview for BCL2L1 抗体 (AA 1-135) (ABIN6936491)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

SPM519
  • 抗原表位

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    AA 1-135

    特异性

    Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human BCL2L1 protein fragment (around aa 1-135) (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat, K562, HL-60 or HeLa cells. Reed-Sternberg cells in Hodgkin's lymphoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    BCL2L1

    背景

    Apoptosis regulator Bcl-X, B cell lymphoma 2 like, BCL XL/S, Bcl-2-like protein 1, Bcl2-L-1, BCL2L, Bcl2l1, BCLX, BclXL, BclXs, Protein phosphatase 1 regulatory subunit 52 (PPP1R52),Bcl-X (Apoptosis Marker)
    Cellular localisation: Cytoplasmic and cell / nuclear membrane

    分子量

    27kDa

    基因ID

    598, 516966

    UniProt

    Q07817

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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