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VDAC1 抗体 (AA 85-190)

Name: VDAC1 抗体 (AA 85-190)
SKU: ABIN686872
Availability: OutOfStock

VDAC1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti VDAC Polyclonal Antibody, Unconjugated (ABIN686872) at 1:200 followed by conjugation to the secondary antibody and DAB staining (VDAC1 抗体 (AA 85-190))

IHC

1 image

(5 references)

产品编号 ABIN686872

发货至: 中国

Datasheet as PDF

抗原 See all VDAC1 抗体

VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
抗原表位
14

12

7

7

5

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 85-190
适用
90

46

36

5

4

4

3

3

3

3

3

2

2

2

2

1

1

1

1

1
人, 大鼠
宿主
74

24
兔
Compatible Secondaries
克隆类型
64

34
多克隆
标记
45

7

6

5

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
This VDAC1 antibody is un-conjugated
应用范围
77

43

34

19

18

12

12

9

5

4

4

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

May detect VDAC2 due to sequence similarity

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human VDAC1

亚型

IgG

Top Product

Discover our top product VDAC1 Primary Antibody
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody
VDAC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-30), (N-Term) antibody
VDAC1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19920 unconjugated

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibody (APC)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal APC

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 unconjugated

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (HRP)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 HRP

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibody (HRP)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal HRP

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (FITC)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 FITC

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibody (Alkaline Phosphatase (AP))
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Biotin)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 Biotin

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PE)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 PE

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Lin, Zhang, Liu, Tan, Ma: "Penehyclidine hydrochloride prevents anoxia/reoxygenation injury and induces H9c2 cardiomyocyte apoptosis via a mitochondrial pathway." in: European journal of pharmacology, Vol. 797, pp. 115-123, (2017) (PubMed).

Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Tan, Chen, Ma: "Penehyclidine hydrochloride post-conditioning reduces ischemia/reperfusion-induced cardiomyocyte apoptosis in rats." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4272-4278, (2017) (PubMed).

Xing, Yuan, Xu, Gu, Liang, Lu: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." in: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, (2015) (PubMed).

Manczak, Reddy: "Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease." in: Human molecular genetics, Vol. 21, Issue 23, pp. 5131-46, (2012) (PubMed).
抗原

VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

别名

VDAC (VDAC1 产品)

别名

vdac1 antibody, VDAC1 antibody, 5076 antibody, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antibody, ATVDAC1 antibody, T22N4.9 antibody, T22N4_9 antibody, voltage dependent anion channel 1 antibody, PORIN antibody, VDAC-1 antibody, AL033343 antibody, Vdac5 antibody, fa13f11 antibody, wu:fa13f11 antibody, zgc:85830 antibody, voltage-dependent anion channel 1 S homeolog antibody, voltage-dependent anion channel 1 antibody, voltage dependent anion channel 1 antibody, vdac1.S antibody, vdac1 antibody, VDAC1 antibody, Vdac1 antibody

背景

Synonyms: PORIN, VDAC-1, Voltage-dependent anion-selective channel protein 1, hVDAC1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC1, VDAC
Background: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

基因ID

7416

UniProt

P21796