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APEX1 抗体 (AA 201-318) (Biotin)

This anti-APEX1 antibody is a 兔 多克隆 antibody detecting APEX1 in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN686094
发货至: 中国

Quick Overview for APEX1 抗体 (AA 201-318) (Biotin) (ABIN686094)

抗原

See all APEX1 抗体
APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

适用

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宿主

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克隆类型

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多克隆

标记

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This APEX1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
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    AA 201-318

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human APEX1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

    别名

    REF1/APEX1

    背景

    Synonyms: mitochondrial, AP endonuclease 1, Ape1, AP endonuclease class I, AP lyase, APE 1, APE, APE-1, APEN, APEX 1, APEX, APEX nuclease multunctional DNA repair enzyme 1, Apex nuclease 1, APEX nuclease, APEX1, APEX1_HUMAN, Apurinic endonuclease, Apurinic-apyrimidinic endonuclease 1, Apurinic/apyrimidinic abasic endonuclease, Apurinic/apyrimidinic endonuclease 1, Apurinic/apyrimidinic exonuclease, APX, BAP1, Deoxyribonuclease apurinic or apyrimidinic, DNA apurinic or apyrimidinic site lyase, DNA-apurinic or apyrimidinic site lyase, DNA-apurinic or apyrimidinic site lyase, mitochondrial, EC 4.2.99.18, HAP 1, HAP1, Human Apurinic endonuclease 1, Apurinic/Apyrimidic eEndonuclease 1, MGC139790, Multunctional DNA repair enzyme, Redox effector factor 1, Redox factor 1, Redox factor-1, REF 1, REF 1 protein, REF-1, REF1, REF1 protein.

    Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein. [provided by RefSeq].

    基因ID

    328

    途径

    DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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