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TP53BP1 抗体 (pSer25, pSer29)

Cited in 1 publication. This anti-TP53BP1 antibody is a 兔 多克隆 antibody detecting TP53BP1 in ELISA, ICC, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN682993
发货至: 中国
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Quick Overview for TP53BP1 抗体 (pSer25, pSer29) (ABIN682993)

抗原

See all TP53BP1 抗体
TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

适用

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人, 小鼠, 大鼠

宿主

  • 102
  • 9
  • 2
  • 1

克隆类型

  • 81
  • 33
多克隆

标记

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This TP53BP1 antibody is un-conjugated

应用范围

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ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 25
    • 15
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    • 7
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    • 3
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    pSer25, pSer29

    特异性

    This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: "Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).

  • 抗原

    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

    别名

    p53BP1 +

    背景

    Synonyms: p202, 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1, TP53BP1

    Background: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

    基因ID

    7158

    UniProt

    Q12888

    途径

    DNA Damage Repair
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