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OXSR1 抗体 (AA 201-300) (Cy5.5)

OXSR1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN681813
发货至: 中国
  • 抗原 See all OXSR1 抗体
    OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 58
    • 19
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 47
    • 11
    克隆类型
    • 49
    • 9
    多克隆
    标记
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OXSR1 antibody is conjugated to Cy5.5
    应用范围
    • 41
    • 31
    • 19
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human OXSR1.
    亚型
    IgG
    Top Product
    Discover our top product OXSR1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))
    别名
    OXSR1 (OXSR1 产品)
    别名
    OSR1 antibody, C20orf111 antibody, HSPC207 antibody, Osr1 antibody, Perit1 antibody, dJ1183I21.1 antibody, zgc:55494 antibody, zgc:77321 antibody, OXSR1 antibody, 2210022N24Rik antibody, 2810422B09Rik antibody, AI462649 antibody, AW209236 antibody, mKIAA1101 antibody, odd1 antibody, osr1 antibody, wu:fb77f12 antibody, zgc:165661 antibody, oxidative stress responsive 1 antibody, oxidative stress responsive serine rich 1 antibody, oxidative stress responsive 1b antibody, serine/threonine-protein kinase OSR1 antibody, odd-skipped related transciption factor 1 antibody, oxidative-stress responsive 1 antibody, oxidative stress responsive 1a antibody, OXSR1 antibody, OSER1 antibody, oxsr1b antibody, CpipJ_CPIJ015177 antibody, Tsp_00299 antibody, OSR1 antibody, Oxsr1 antibody, LOC106505565 antibody, oxsr1 antibody, oxsr1a antibody
    背景

    Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.

    Background: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.

    基因ID
    9943
    途径
    Tube Formation
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