PCNA 抗体 (AA 201-261)
Quick Overview for PCNA 抗体 (AA 201-261) (ABIN676598)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-261
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交叉反应
- 小鸡, 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PCNA
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亚型
- IgG
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anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 151-261) antibody
PCNA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) antibodyPCNA 适用: 人 WB, IHC, IF, IHC (p), IP, ICC, IHC (fro), FISH 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 53-196) antibodyPCNA 适用: 人, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7H4F8 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 6-261) antibodyPCNA 适用: 人, 小鼠, 大鼠, Pig, 犬, 兔, 猕猴 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) antibodyPCNA 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H10 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) antibodyPCNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 231-261), (C-Term) antibodyPCNA 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17486 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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别名
- PCNA
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背景
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Synonyms: ATLD2, Proliferating cell nuclear antigen, PCNA, Cyclin
Background: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
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基因ID
- 5111
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UniProt
- P12004
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
抗原
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