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BCL2L1 抗体 (pSer62)

This anti-BCL2L1 antibody is a 兔 多克隆 antibody detecting BCL2L1 in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN675144
发货至: 中国

Quick Overview for BCL2L1 抗体 (pSer62) (ABIN675144)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    pSer62

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Bcl-xL around the phosphorylation site of Ser62

    亚型

    IgG
  • 应用备注

    WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    Bcl-Xl/Bcl2l1

    背景

    Synonyms: BCL2L1 phospho S62, p-BCL2L1 phospho S62,Apoptosis regulator Bcl X, BclX, Bcl-X, Bcl 2 like 1, Bcl 2 like 1 protein, Bcl xL, BCL X/L, BCL XL/S, Bcl xS, Bcl2 like1, BCL2-related gene, BCL2-related protein, long isoform, included, BCLXL, included, BCL2-related protein, short isoform, included, BCLXS, included, BCL2L, BCL2L1, Bclx, DKFZp781P2092, MGC113803, MGC99998, B2CL1_HUMAN.

    Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].

    基因ID

    598

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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