PPP1R13B 抗体 (AA 901-1090)
(1 reference)Quick Overview for PPP1R13B 抗体 (AA 901-1090) (ABIN674379)
抗原
See all PPP1R13B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 901-1090
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Dog,Cow,Horse,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human ASPP1
-
亚型
- IgG
-
-
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (AA 630-680) antibody
PPP1R13B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (AA 375-675) antibodyPPP1R13B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (AA 1-90) antibodyPPP1R13B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H1 unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (Internal Region) antibodyPPP1R13B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (AA 900-949) antibodyPPP1R13B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) antibodyPPP1R13B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (Middle Region) antibodyPPP1R13B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
-
: "Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study." in: Chinese journal of cancer, Vol. 36, Issue 1, pp. 15, (2017) (PubMed).
-
: "Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study." in: Chinese journal of cancer, Vol. 36, Issue 1, pp. 15, (2017) (PubMed).
-
- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
-
别名
- ASPP1
-
背景
-
Synonyms: p53BP2 like, p85, PPP1R13B, apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51.
Background: iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51.
-
基因ID
- 23368
-
UniProt
- Q96KQ4
-
途径
- p53 Pathway
抗原
-
