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TRADD 抗体 (AA 111-230)

Cited in 1 publication. This anti-TRADD antibody is a 兔 多克隆 antibody detecting TRADD in WB, ELISA, IHC (p), IHC (fro), IF (cc) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN673314
发货至: 中国
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Quick Overview for TRADD 抗体 (AA 111-230) (ABIN673314)

抗原

See all TRADD 抗体
TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

适用

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人, 小鼠, 大鼠

宿主

  • 46
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克隆类型

  • 35
  • 14
多克隆

标记

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This TRADD antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 7
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    AA 111-230

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse of mouse TRADD

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Chen, Zhang, Zhang, Li, Sun: "Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling." in: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1304-9, (2016) (PubMed).

  • 抗原

    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

    别名

    TRADD

    背景

    Synonyms: AA930854, 9130005N23Rik, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tradd

    Background: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

    基因ID

    71609

    UniProt

    Q3U0V2

    途径

    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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