The clone OTH-74D4 recognizes a 220 kD isoform of the leucocyte common antigen (LCA) of the CD45 antigen family. The CD45RA antigen is expressed mostly on naive CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation. The CD45RA expression on immune cells is used as one of the key surface antigen to determine the functional status and also to define the end-stage of human T cells.
纯化方法
Purified
纯度
>95 %
质量等级
GMP Grade
免疫原
An EBV-transformed B cell line from a patient with MHC class II deficiency
B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Lca antibody, RT7 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, PTPRC antibody, Ptprc antibody
背景
The clone OTH-74D4 recognizes a 220 kD isoform of the leucocyte common antigen (LCA) of the CD45 antigen family. The CD45RA antigen is expressed mostly on naive CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation. The CD45RA expression on immune cells is used as one of the key surface antigen to determine the functional status and also to define the end-stage of human T cells.