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SLC11A1 抗体 (AA 183-549)

SLC11A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6719517
发货至: 中国
  • 抗原 See all SLC11A1 抗体
    SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
    抗原表位
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-549
    适用
    • 31
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 28
    • 4
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 22
    • 4
    • 2
    • 2
    • 1
    • 1
    This SLC11A1 antibody is un-conjugated
    应用范围
    • 26
    • 16
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for NRAMP1/SLC11A1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for NRAMP1/SLC11A1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human NRAMP1/SLC11A1 recombinant protein (Position: F183-S549).
    亚型
    IgG
    Top Product
    Discover our top product SLC11A1 Primary Antibody
  • 应用备注

    Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
    别名
    SLC11A1 (SLC11A1 产品)
    别名
    SLC11A1 antibody, NRAMP1 antibody, LSH antibody, NRAMP antibody, Bcg antibody, Itg antibody, Lsh antibody, Nramp1 antibody, Ity antibody, Nramp antibody, ity antibody, BCG antibody, solute carrier family 11 member 1 L homeolog antibody, solute carrier family 11 member 1 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 antibody, slc11a1.L antibody, SLC11A1 antibody, Slc11a1 antibody
    背景

    Synonyms: Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1, SLC11A1, LSH, NRAMP, NRAMP1

    Background: Natural resistance-associated macrophage protein 1 is a protein that in humans is encoded by the SLC11A1gene. It is mapped to 2q35. This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

    基因ID
    6556
    UniProt
    P49279
    途径
    Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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