Connexin 43/GJA1 抗体 (C-Term)
Quick Overview for Connexin 43/GJA1 抗体 (C-Term) (ABIN6658278)
抗原
See all Connexin 43/GJA1 (GJA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 612-401-d22
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Supplier
- Rockland
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原理
- Connexin 43 Antibody
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交叉反应 (详细)
- Anti-Connexin 43 antibody is directed against rat Connexin 43
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纯化方法
- .Anti-Connexin 43 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Connexin 43 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Connexin 43 Antibody has been tested by western blot and is suitable for use in ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 43 kDa in size corresponding to connexin 43 protein in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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别名
- Connexin 43
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背景
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Synonyms: Gap junction alpha-1 protein, Gap junction 43 kDa heart protein, CX43
Background: Connexin 43 Antibody detects connexin which is thought to play a key role in development and may also be involved in epilepsy. Connexin 43 antibody recognizes Connexin 43 which forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C. Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability. Anti-Connexin 43 Antibody is ideal for investigators involved in Neuroscience and Cell Signaling.
Gene Name: GJA1
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基因ID
- 24392
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UniProt
- P08050
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途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
抗原
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