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KCNA1 抗体 (Extracellular Domain)

KCNA1 适用: 大鼠 WB, IHC, FM 宿主: 小鼠 Monoclonal S36-15 unconjugated
产品编号 ABIN6658238
发货至: 中国
  • 抗原 See all KCNA1 抗体
    KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 74
    • 23
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 72
    • 6
    小鼠
    克隆类型
    • 74
    • 4
    单克隆
    标记
    • 31
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNA1 antibody is un-conjugated
    应用范围
    • 53
    • 30
    • 20
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    交叉反应
    小鼠, 大鼠
    纯化方法
    Anti-Kv1.1 Extracellular Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.1 from Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.1 from other sources has not been determined. Ion Channels research.
    免疫原

    Immunogen: Kv1.1 Extracellular Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at an extracellular domain of rat Kv1.1.

    Immunogen Type: Peptide

    克隆位点
    S36-15
    亚型
    IgG2b
    Top Product
    Discover our top product KCNA1 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 0.1-1.0 μg/mL

    Application Note: Anti-Kv1.1 Extracellular Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~56 kDa (could be 65-85 depending on glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1 μg/mL

    IF Microscopy Dilution: 1.0-10 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
    别名
    Kv1.1 (KCNA1 产品)
    别名
    AEMK antibody, EA1 antibody, HBK1 antibody, HUK1 antibody, KV1.1 antibody, MBK1 antibody, MK1 antibody, RBK1 antibody, KCNA1 antibody, AI840627 antibody, Kca1-1 antibody, Kv1.1 antibody, Mk-1 antibody, Shak antibody, mceph antibody, Kcna antibody, Kcpvd antibody, potassium voltage-gated channel subfamily A member 1 antibody, potassium voltage-gated channel, shaker-related subfamily, member 1 antibody, fragile site, aphidicolin type, common, fra(12)(q24) antibody, KCNA1 antibody, Kcna1 antibody, FRA12E antibody
    背景

    Synonyms: KCA1, KCNA1, MBK1, MK1, RBK1, Shak, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage gated channel subfamily A member 1, RBKI, RCK1

    Background: Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.

    Gene Name: Kcna1

    基因ID
    24520
    NCBI登录号
    NP_775118
    UniProt
    P10499
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