GABRA2 抗体 (Cytoplasmic Loop)
(1 reference)-
- 抗原 See all GABRA2 抗体
- GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))
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抗原表位
- Cytoplasmic Loop
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Cross reactivity to GABA(A) from other species has not been determined.
- 纯化方法
- Anti-GABA(A) Receptor alpha 2 antibody is directed against rat GABA(A) receptor alpha 2 protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Labeling is absent in α2-subunit knockout animals. Reactivity is expected from bovine, canine, human, non-human primate, Zebrafish.
- 免疫原
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Immunogen: Anti-GABA(A) Receptor alpha 2 Antibody was produced in rabbit by repeated immunizations with a fusion protein from the cytoplasmic loop of the rat receptor alpha 2 subunit.
Immunogen Type: Recombinant Protein
- 亚型
- IgG
- Top Product
- Discover our top product GABRA2 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 185-280) antibody
GABRA2 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (N-Term) antibodyGABRA2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 300-400) antibodyGABRA2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 42-250) antibodyGABRA2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 29-251) antibodyGABRA2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (Cytoplasmic Loop) antibodyGABRA2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 378-406), (C-Term) antibodyGABRA2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23934 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (AA 29-37) antibodyGABRA2 适用: 人, 小鼠, 大鼠 WB, ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (Center) antibodyGABRA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) (Middle Region) antibodyGABRA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-GABA(A) Receptor alpha 2 (Rabbit) Antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 51 kDa in size corresponding to the alpha 2 subunit of the GABA(A) receptor in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).
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: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).
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- 抗原
- GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))
- 别名
- GABA(A) Receptor alpha 2 (GABRA2 产品)
- 别名
- C630048P16Rik antibody, Gabra-2 antibody, gamma-aminobutyric acid type A receptor alpha2 subunit antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 antibody, GABRA2 antibody, GABRA1 antibody, gabra2 antibody, Gabra2 antibody, gabra2.S antibody
- 背景
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Synonyms: Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2
Background: GABA(A) Receptor alpha 2 Antibody detects GABA(A) receptor alpha 2 protein. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. GABA(A) receptor alpha 2 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRA2
- 基因ID
- 61856
- NCBI登录号
- NP_001129251
- UniProt
- P23576
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