GABRB3 抗体 (pSer408, pSer409)
(1 reference)-
- 抗原 See all GABRB3 抗体
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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抗原表位
- pSer408, pSer409
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠
- 纯化方法
- Anti-GABA(A) Receptor beta 3 pS408/pS409 Antibody is directed against rat GABA(A) Receptor beta 3. The antibody was affinity purified from monospecific antiserum by immunoaffintiy purification. Immunolabeling of the GABAA band is completely blocked by the phospho-peptide used as antigen but not by the corresponding dephospho-peptide. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, chicken, human, mouse, non-human primates, Xenopus and zebra fish.
- 免疫原
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Immunogen: Anti-GABA(A) Receptor beta 3 pS408/pS409 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser408/409.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product GABRB3 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (AA 328-450) antibody
GABRB3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (AA 344-429) antibodyGABRB3 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (AA 180-229) antibodyGABRB3 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (AA 370-433) antibodyGABRB3 适用: 小鼠 WB, IHC (p), ICC, IF 宿主: 小鼠 Monoclonal S87-25 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (pSer408), (pSer409) antibodyGABRB3 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Cytoplasmic Loop) antibodyGABRB3 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (AA 344-429) antibodyGABRB3 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) antibodyGABRB3 适用: 大鼠, 小鼠 WB, ICC, IP 宿主: 小鼠 Monoclonal 261F6 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Internal Region) antibodyVerified GABRB3 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Middle Region) antibodyGABRB3 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-GABA(A) Receptor beta 3 pS408/pS409 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 53 kDa in size corresponding to GABA(A) receptor beta 3 subunit phosphorylated at Ser408/409 in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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: "TNF-? downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 40, pp. 15879-93, (2013) (PubMed).
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: "TNF-? downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 40, pp. 15879-93, (2013) (PubMed).
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- 抗原
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- 别名
- GABA(A) Receptor beta 3 (GABRB3 产品)
- 别名
- GABRB3 antibody, eca5 antibody, LOC100230475 antibody, ECA5 antibody, A230092K12Rik antibody, AW049585 antibody, Cp1 antibody, Gabrb-3 antibody, beta3 antibody, gamma-aminobutyric acid type A receptor beta3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 3 antibody, gamma-aminobutyric acid type A receptor beta 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antibody, GABRB3 antibody, gabrb3 antibody, Gabrb3 antibody
- 背景
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Synonyms: Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, Gabrb3, GABA(A) receptor subunit ß-3
Background: Anti-GABA(A) Receptor beta 3 pS408/pS409 Antibody detects GABA(A) Receptor beta 3. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma- subunit is required for benzodiazepine modulation. Phosphorylation of serine 408 and serine 409 within the beta3 subunit have been shown to be critical for the functional modulation of beta3 containing recombinant receptors. GABA(A) Receptor beta 3 pS408/pS409 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRB3
- 基因ID
- 24922
- UniProt
- P63079
- 途径
- Sensory Perception of Sound
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