NOX1 抗体 (Internal Region)
Quick Overview for NOX1 抗体 (Internal Region) (ABIN6658038)
抗原
See all NOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-r15
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Supplier
- Rockland
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原理
- Nox1 Antibody
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交叉反应 （详细）
- Anti-NOX1 antibody is directed against rat NOX1 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- NOX1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of rat NOX1.
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亚型
- IgG
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anti-NADPH Oxidase 1 (NOX1) antibody
NOX1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 235-488) antibodyNOX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (Internal Region) antibodyVerified NOX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 291-544) antibodyNOX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 418-564) antibodyNOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 425-515) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 200-300) antibodyNOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 354-374), (Middle Region) antibodyNOX1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5 μg/mL
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说明
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Anti-NOX1 is tested in Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~65.2 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- NOX1 (NADPH Oxidase 1 (NOX1))
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别名
- NOX1
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背景
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Synonyms: Mitogenic oxidase 1,
Background: NOX1(NADPH OXIDASE 1), also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. The NOX1 gene is mapped to Xq22.1. NOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid NOX1 protein, which is 58 % identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing MOX1 had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50 % survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion. This antibody is suitable for researchers interested in epigenetic antibodies and cancer research.
Gene Name: NOX1
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基因ID
- 114243
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NCBI登录号
- NP_446135
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UniProt
- Q9WV87
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
抗原
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