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PAK1 抗体 (pThr84)

This anti-PAK1 antibody is a 兔多克隆 antibody detecting PAK1 in WB 和 ELISA. Suitable for 人.

产品编号 ABIN6656323

Supplier Product No.: 600-401-x21

发货至: 中国

Quick Overview for PAK1 抗体 (pThr84) (ABIN6656323)

抗原

See all PAK1 抗体

PAK1 (P21-Activated Kinase 1 (PAK1))

适用

173
92
80
7
5
5
4
4
3
2
1
1

人

宿主

兔

克隆类型

多克隆

标记

91
8
6
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3

This PAK1 antibody is un-conjugated

应用范围

112
61
47
39
39
34
30
13
11
10
9
4
3
3
2
1

Western Blotting (WB), ELISA

Discover our top product PAK1 Primary Antibody

抗原表位
28

22

15

13

11

9

8

8

7

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr84

Supplier Product No.

600-401-x21

Supplier

Rockland

原理

PAK 1 Phospho T84 Antibody

交叉反应（详细）

Anti-Phospho-Thr84 PAK1 Antibody is directed against PAK1 protein phosphorylated at T84.

纯化方法

The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

过滤

Sterile filtered

免疫原

Anti-Phospho-Thr84 PAK1 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding the phospho-Thr84 of human PAK1 conjugated to KLH.

亚型

IgG
anti-P21-Activated Kinase 1 (PAK1) (AA 191-280) antibody
PAK1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 4D1 unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Center) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibody
PAK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibody
PAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibody
PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Ser204) antibody
PAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 245-490) antibody
PAK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr423) antibody
PAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB11381 unconjugated

应用备注

ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000

说明

Anti-Phospho-Thr84 PAK1 Antibody is tested for Western Blots and is specific for the ~68 kDa PAK1 phosphorylated at Thr84. Specific conditions for reactivity should be optimized by the end user.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None

储存液

Without preservative

储存条件

-20 °C

储存方法

Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

有效期

12 months
抗原

PAK1 (P21-Activated Kinase 1 (PAK1))

别名

PAK1

背景

Synonyms: Serine/Threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, p65-PAK
Background: PAKs, p21 activated kinases, are a family of serine/threonine protein kinases comprised of six isoforms, PAK1-6, and they play important roles in cytoskeleton dynamics, cell survival and proliferation. Each of these isoforms contains a C-terminal catalytic domain and an N-terminal regulatory domain with a small G protein binding motif. OSR1, oxidative stress response 1, is activated only by osmotic stresses, like sorbital or NaCl. It has been predicted that OSR1 phosphorylates PAK1 in the regulatory domain at thr84 and inhibits activation of JNK and MAPK pathway. It has also been suggested that OSR1 may have a regulating function with actin cytoskeleton because it can phosphorylate PAK1 at thr84 and bind to gelsolin. PAK1 pT84 Antibody is ideal for researchers interested in cell cycle research.
Gene Name: PAK1

基因ID

5058

NCBI登录号

NP_001122092

UniProt

Q13153

途径

MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis

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