Caspase 1 抗体 (C-Term)
Quick Overview for Caspase 1 抗体 (C-Term) (ABIN6655699)
抗原
See all Caspase 1 (CASP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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Supplier Product No.
- 200-301-h62
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Supplier
- Rockland
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原理
- Caspase-1 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-Caspase-1 from human and mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Caspase-1 Antibody was purified by Protein G chromatography.
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免疫原
- Caspase-1 Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to amino acids near the c-terminus of the immunogen, human Caspase-1.
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亚型
- IgG1 kappa
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anti-Caspase 1 (CASP1) (AA 120-297) antibody
CASP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 317-404) antibodyCASP1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 119-296) antibodyCASP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 适用: Pig WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-311) antibodyCASP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-100) antibodyCASP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Caspase 1 (CASP1) antibodyCASP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibodyCASP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100 - 1:500
Western_Blot_Dilution: 0.5-2 μg/mL
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说明
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Anti-Caspase-1 antibody has been tested in IHC-F, IHC-P, IF, and WB. Expect a band approximately 46kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Caspase 1 (CASP1)
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别名
- Caspase-1
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背景
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Synonyms: IL1BC, IL1BCE, Caspase-1, CASP-1, 3.4.22.36, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p20, Caspase-1 subunit p10
Background: Anti-Caspase-1 detects human Caspase. Caspase proteins are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspase proteins is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into tetramer to form the active enzyme. Caspase-1 (ICE, IL-1b converting enzyme) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates multiple proinflammatory cytokines, including interleukin-1b and interferon-gamma-inducing factor. Anti-Caspase-1 antibody is ideal for investigators involved in apoptosis research.
Gene Name: CASP1
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基因ID
- 834
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NCBI登录号
- NP_001214
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UniProt
- P29466
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途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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