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- 抗原 See all IGKV1-27 抗体
- IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGKV1-27 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 纯化方法
- Anti-A20 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-A20 from Human, Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-A20 from other sources has not been determined.
- 免疫原
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Immunogen: A20 Antibody was produced in mice by repeated immunizations with recombinant human A20 protein at the c-terminus.
Immunogen Type: Recombinant Protein
- 克隆位点
- 59A426
- 亚型
- IgG1
- Top Product
- Discover our top product IGKV1-27 Primary Antibody
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anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Internal Region) antibody
IGKV1-27 适用: 人, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Center) antibodyIGKV1-27 适用: 人, 小鼠, 大鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-A20 antibody is suitable for use in Flow (I), IF/ICC, IHC (p), IP and WB. Expect a band approximately 90 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: 1-2 μg/mL
Western Blot Dilution: 2-4 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))
- 别名
- A20 (IGKV1-27 产品)
- 别名
- A20 antibody, OTUD7C antibody, TNFA1P2 antibody, TNF alpha induced protein 3 antibody, TNFAIP3 antibody
- 背景
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Synonyms: OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, A20p50, A20p37
Background: Anti-A20 antibody detects human A20. A20 (TNFAIP3) is an important regulator of proinflammatory signaling pathways, including NK-kB sginaling. A20 is upregulated through NF-kB (p50/p55) activation, and subsequently down regulates NF-kB through its dual function as a deubiquitinase and ubiquitin ligase. The A20 monoclonal antibody has been instrumental in discovering various nuances of NF-kB regulation and key to defining A20 biology. Anti-A20 antibody is ideal for investigators involved in NFkappaB and Signaling research.
Gene Name: TNFAIP3
- 基因ID
- 7128
- NCBI登录号
- NP_001257436
- UniProt
- P21580
- 途径
- Activation of Innate immune Response
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