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PARP1 抗体 (Cleavage Site)

Name: PARP1 抗体 (Cleavage Site)
SKU: ABIN6655433
Availability: OutOfStock

PARP1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 194C1439 unconjugated

PARP Western Blot. (PARP1 抗体 (Cleavage Site))

1 image

产品编号 ABIN6655433

Supplier Product No.: 200-301-i03

发货至: 中国

Datasheet as PDF

抗原 See all PARP1 抗体

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
抗原表位
16

15

15

10

8

8

8

8

8

8

8

7

7

7

7

7

6

5

5

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cleavage Site
适用
217

56

43

8

6

5

4

4

4

4

4

2

2

1

1
人
宿主
213

21

1
小鼠
Compatible Secondaries
克隆类型
206

29
单克隆
标记
133

16

15

13

12

12

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This PARP1 antibody is un-conjugated
应用范围
146

118

69

31

31

25

25

22

21

17

16

7

7

4

3

2

2

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Supplier Product No.

200-301-i03

Supplier

Rockland

原理

PARP Antibody

交叉反应（详细）

A BLAST analysis was used to suggest cross-reactivity with Anti-PARP from human based on 100 % homology with the immunizing sequence.

纯化方法

Anti-PARP Antibody was purified by Protein G chromatography.

免疫原

PARP Antibody was produced in mice prepared by repeated immunizations with a peptide containing amino acids near the 214/215 cleavage site of human PARP protein.

克隆位点

194C1439

亚型

IgG2b kappa

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anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibody
PARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibody
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PARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibody
PARP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
PARP1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibody
PARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibody
PARP1 适用: 人 WB, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibody
PARP1 适用: 人 WB, IHC, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

应用备注

Flow_Cytometry_Dilution: 1-3 μg/test
Western_Blot_Dilution: 1-2 μg/mL

说明

Anti-PARP antibody is tested for use in WB, Flow, Flow-IC, and ICC/IF. Expect a band approximately 89kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
抗原

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

别名

PARP (PARP1 产品)

背景

Synonyms: ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, PARP-1, 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1
Background: Anti-PARP antibody detects human PARP. The poly (ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP [Poly (ADP-ribose) polymerase] is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa-fragment irreversibly bind to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks. Anti-PARP antibody is ideal for investigators involved in Apoptosis, DNA damage and Repair research.
Gene Name: PARP1

基因ID

142

NCBI登录号

NP_001609

UniProt

P09874

途径

Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location