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Grancalcin 抗体 (AA 42-217)

GCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6654161
发货至: 中国
  • 抗原 See all Grancalcin (GCA) 抗体
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-217
    适用
    • 13
    • 5
    • 2
    宿主
    • 11
    • 3
    克隆类型
    • 11
    • 3
    多克隆
    标记
    • 14
    This Grancalcin antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids A42-I217 from the human protein were used as the immunogen for the Grancalcin antibody.
    亚型
    IgG
    Top Product
    Discover our top product GCA Primary Antibody
  • 应用备注
    Optimal dilution of the Grancalcin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Grancalcin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    别名
    Grancalcin / GCA (GCA 产品)
    别名
    Grancalcin antibody, 5133401E04Rik antibody, AI573844 antibody, GCL antibody, zgc:92027 antibody, grancalcin antibody, Grancalcin antibody, zgc:92027 antibody, GCA antibody, gran antibody, LOC100280890 antibody, Gca antibody
    背景
    Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
    UniProt
    P28676
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