XPO1 抗体 (AA 966-1071)
Quick Overview for XPO1 抗体 (AA 966-1071) (ABIN6654156)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 966-1071
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纯化方法
- Protein G affinity
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免疫原
- Human Exportin-1 recombinant protein (amino acids N966-D1071) was used as the immunogen for the XPO1 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the XPO1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the XPO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- XPO1 (Exportin 1 (XPO1))
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别名
- XPO1
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背景
- Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.
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UniProt
- O14980
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途径
- M Phase
抗原
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