DDR2 抗体 (AA 801-855)
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Quick Overview for DDR2 抗体 (AA 801-855) (ABIN6654123)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 801-855
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids T801-E855 from the human protein were used as the immunogen for the DDR2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the DDR2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 2-3 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the DDR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- DDR2
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背景
- Discoidin domain-containing receptor 2, also known as CD167b (cluster of differentiation 167b), is a protein that in humans is encoded by the DDR2 gene. This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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