DDR2 抗体
(Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| DDR2 抗体 | 人 | 小鼠 Monoclonal |
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| DDR2 抗体 | 人 | 兔 Polyclonal |
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| DDR2 抗体 (AA 245-350) | 人 | 兔 Polyclonal |
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| DDR2 抗体 (AA 578-817) | 人 | 兔 Polyclonal |
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| DDR2 抗体 (AA 447-540) | 人 | 兔 Polyclonal |
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| DDR2 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| DDR2 抗体 | 人 | 兔 Polyclonal |
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| DDR2 抗体 | 人 | 兔 Polyclonal |
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| Recombinant DDR2 抗体 | 人 | 兔 Monoclonal |
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| DDR2 抗体 (AA 290-400) | 人 | 兔 Polyclonal |
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| DDR2 抗体 | 人 | 兔 Monoclonal |
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| DDR2 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| DDR2 抗体 (AA 290-320) | 人 | 兔 Polyclonal |
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| DDR2 抗体 (AA 290-320) | 人 | 小鼠 Monoclonal |
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| DDR2 抗体 (AA 277-377) | 人 | 小鼠 Polyclonal |
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| DDR2 抗体 (AA 816-843) | 小鼠 | 兔 Polyclonal |
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| DDR2 抗体 (AA 290-320) | 人 | 小鼠 Monoclonal |
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| DDR2 抗体 (AA 24-399) | 人 | 兔 Polyclonal |
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| DDR2 抗体 (AA 816-843) (PE) | 小鼠 | 兔 Polyclonal |
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| DDR2 抗体 (AA 816-843) (APC) | 小鼠 | 兔 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
3 references - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3B11E4
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB17713
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 245-350
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 578-817
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 447-540
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB2210
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 290-400
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB01473
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 290-320
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 484CT5-5-4
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 290-320
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 277-377
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 816-843
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3E5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 290-320
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 24-399
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 816-843
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 816-843
Latest Publications for our DDR2 抗体
: "Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction." in: Theranostics, Vol. 9, Issue 22, pp. 6550-6567, (2019) (PubMed).
: "NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4." in: American journal of physiology. Heart and circulatory physiology, Vol. 309, Issue 9, pp. H1528-42, (2015) (PubMed).
: "Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation." in: Circulation research, Vol. 115, Issue 7, pp. 625-35, (2014) (PubMed).
: "Angiotensin II upregulates K(Ca)3.1 channels and stimulates cell proliferation in rat cardiac fibroblasts." in: Biochemical pharmacology, Vol. 85, Issue 10, pp. 1486-94, (2013) (PubMed).
: "The discoidin domain receptor DDR2 is a receptor for type X collagen." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 25, Issue 6, pp. 355-64, (2006) (PubMed).
: "Regulation of discoidin domain receptor 2 by cyclic mechanical stretch in cultured rat vascular smooth muscle cells." in: Hypertension, Vol. 46, Issue 3, pp. 614-21, (2005) (PubMed).
: "Cloning and sequencing of protein kinase cDNA from harbor seal (Phoca vitulina) lymphocytes." in: Clinical & developmental immunology, Vol. 11, Issue 2, pp. 157-63, (2004) (PubMed).
: "The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism." in: EMBO reports, Vol. 2, Issue 5, pp. 446-52, (2001) (PubMed).
: "NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4." in: American journal of physiology. Heart and circulatory physiology, Vol. 309, Issue 9, pp. H1528-42, (2015) (PubMed).
: "Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation." in: Circulation research, Vol. 115, Issue 7, pp. 625-35, (2014) (PubMed).
: "Angiotensin II upregulates K(Ca)3.1 channels and stimulates cell proliferation in rat cardiac fibroblasts." in: Biochemical pharmacology, Vol. 85, Issue 10, pp. 1486-94, (2013) (PubMed).
: "The discoidin domain receptor DDR2 is a receptor for type X collagen." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 25, Issue 6, pp. 355-64, (2006) (PubMed).
: "Regulation of discoidin domain receptor 2 by cyclic mechanical stretch in cultured rat vascular smooth muscle cells." in: Hypertension, Vol. 46, Issue 3, pp. 614-21, (2005) (PubMed).
: "Cloning and sequencing of protein kinase cDNA from harbor seal (Phoca vitulina) lymphocytes." in: Clinical & developmental immunology, Vol. 11, Issue 2, pp. 157-63, (2004) (PubMed).
: "The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism." in: EMBO reports, Vol. 2, Issue 5, pp. 446-52, (2001) (PubMed).
Aliases for DDR2 抗体
discoidin domain receptor tyrosine kinase 2 (DDR2) 抗体discoidin domain receptor family, member 2 (Ddr2) 抗体
discoidin domain receptor tyrosine kinase 2 (Ddr2) 抗体
discoidin domain receptor family, member 2, like (ddr2l) 抗体
AW495251 抗体
DDR2 抗体
ddr2 抗体
MIG20a 抗体
NTRKR3 抗体
Ntrkr3 抗体
si:ch211-193c2.1 抗体
TKT 抗体
TYRO10 抗体
tyro10 抗体
Tyro10 抗体
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