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DDR2 抗体

The 兔 多克隆 anti-DDR2 antibody (ABIN3030741) specifically detects DDR2 in WB, ELISA, IHC 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN3030741
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDR2 抗体 (ABIN3030741)

抗原

See all DDR2 抗体
DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

适用

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宿主

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克隆类型

  • 43
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多克隆

标记

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This DDR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 纯化方法

    Purified

    免疫原

    This DDR2 antibody was produced from rabbits immunized with a his tag recombinant protein of human DDR2/TYRO10.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DDR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

    别名

    DDR2 (TYRO10)

    背景

    DDR2/TYRO10 is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. [UniProt]

    UniProt

    Q16832

    途径

    RTK signaling
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