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CASR 抗体 (AA 926-1078)

The 小鼠 单克隆 anti-CASR antibody (Clone 11E9-) (ABIN6654119) specifically detects CASR in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6654119
发货至: 中国
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Quick Overview for CASR 抗体 (AA 926-1078) (ABIN6654119)

抗原

See all CASR 抗体
CASR (Calcium-Sensing Receptor (CASR))

适用

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宿主

  • 98
  • 7
  • 1
小鼠

克隆类型

  • 100
  • 6
单克隆

标记

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This CASR antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

11E9-
  • 抗原表位

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    AA 926-1078

    纯化方法

    Protein G affinity

    免疫原

    Human CASR recombinant protein (amino acids Q926-S1078) was used as the immunogen for the CASR antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the CASR antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL (human),Flow Cytometry: 1-3 μg/1x10^6 cells (mouse)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CASR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CASR (Calcium-Sensing Receptor (CASR))

    别名

    Calcium Sensing Receptor / CASR

    背景

    The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

    UniProt

    P41180

    途径

    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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