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CASR 抗体 (C-Term)

CASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260407
发货至: 中国
  • 抗原 See all CASR 抗体
    CASR (Calcium-Sensing Receptor (CASR))
    抗原表位
    • 22
    • 20
    • 14
    • 8
    • 5
    • 5
    • 3
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    • 3
    • 2
    • 2
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    C-Term
    适用
    • 85
    • 45
    • 37
    • 8
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    人, 小鼠, 大鼠
    宿主
    • 86
    • 12
    克隆类型
    • 88
    • 10
    多克隆
    标记
    • 45
    • 8
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    • 5
    • 3
    • 3
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    This CASR antibody is un-conjugated
    应用范围
    • 79
    • 33
    • 22
    • 17
    • 17
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Calcium Sensing Receptor Antibody detects endogenous levels of total Calcium Sensing Receptor.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Calcium Sensing Receptor, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CASR Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CASR (Calcium-Sensing Receptor (CASR))
    别名
    CASR (CASR 产品)
    别名
    CAR antibody, EIG8 antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, HYPOC1 antibody, NSHPT antibody, PCAR1 antibody, CaR antibody, Gprc2a antibody, gprc2a antibody, xV2R F-1 antibody, CASR antibody, calcium sensing receptor antibody, calcium-sensing receptor antibody, calcium-sensing receptor L homeolog antibody, CASR antibody, Casr antibody, casr.L antibody
    背景

    Description: G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:7759551, PubMed:8702647, PubMed:8636323, PubMed:8878438, PubMed:17555508, PubMed:19789209, PubMed:21566075, PubMed:22114145, PubMed:23966241, PubMed:25292184, PubMed:25104082, PubMed:26386835, PubMed:25766501, PubMed:22789683). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:7759551). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation (PubMed:27434672, PubMed:27386547).

    Gene: CASR

    分子量
    140kDa
    基因ID
    846
    UniProt
    P41180
    途径
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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