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CASR 抗体 (AA 874-1088)

CASR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1678994
发货至: 中国
  • 抗原 See all CASR 抗体
    CASR (Calcium-Sensing Receptor (CASR))
    抗原表位
    • 22
    • 20
    • 14
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 874-1088
    适用
    • 85
    • 46
    • 38
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 86
    • 12
    克隆类型
    • 88
    • 10
    多克隆
    标记
    • 45
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CASR antibody is un-conjugated
    应用范围
    • 79
    • 34
    • 23
    • 18
    • 17
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PSRNTIEEVR CSTAAHAFKV AARATLRRSN VSRKRSSSLG GSTGSTPSSS ISSKSNSEDP FPQPERQKQQ QPLALTQQEQ QQQPLTLPQQ QRSQQQPRCK QKVIFGSGTV TFSLSFDEPQ KNAMAHRNST HQNSLEAQKS SDTLTRHQPL LPLQCGETDL DLTVQETGLQ GPVGGDQRPE VEDPEELSPA LVVSSSQSFV ISGGGSTVTE NVVNS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 874-1088 of human CASR (NP_001171536.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Xiao, Su, Feng, Sun, Liu, Zhang, Lu, Li, Wang, Zhu, Hu: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." in: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).

  • 抗原
    CASR (Calcium-Sensing Receptor (CASR))
    别名
    CASR (CASR 产品)
    别名
    CAR antibody, EIG8 antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, HYPOC1 antibody, NSHPT antibody, PCAR1 antibody, CaR antibody, Gprc2a antibody, gprc2a antibody, xV2R F-1 antibody, CASR antibody, calcium sensing receptor antibody, calcium-sensing receptor antibody, calcium-sensing receptor L homeolog antibody, CASR antibody, Casr antibody, casr.L antibody
    背景
    The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.,CASR,CAR,EIG8,FHH,FIH,GPRC2A,HHC,HHC1,HYPOC1,NSHPT,PCAR1,hCasR,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Endocrine & Metabolism,Neuroscience,Calcium Signaling,CASR
    分子量
    120 kDa/121 kDa
    基因ID
    846
    UniProt
    P41180
    途径
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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