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CASR 抗体

CASR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7246118
发货至: 中国
  • 抗原 See all CASR 抗体
    CASR (Calcium-Sensing Receptor (CASR))
    适用
    • 85
    • 46
    • 38
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
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    • 1
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    宿主
    • 86
    • 12
    克隆类型
    • 88
    • 10
    多克隆
    标记
    • 45
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    • 5
    • 3
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    This CASR antibody is un-conjugated
    应用范围
    • 80
    • 33
    • 23
    • 18
    • 17
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
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    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human CASR
    亚型
    IgG
    Top Product
    Discover our top product CASR Primary Antibody
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CASR (Calcium-Sensing Receptor (CASR))
    别名
    CASR (CASR 产品)
    别名
    CAR antibody, EIG8 antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, HYPOC1 antibody, NSHPT antibody, PCAR1 antibody, CaR antibody, Gprc2a antibody, gprc2a antibody, xV2R F-1 antibody, CASR antibody, calcium sensing receptor antibody, calcium-sensing receptor antibody, calcium-sensing receptor L homeolog antibody, CASR antibody, Casr antibody, casr.L antibody
    背景
    CASR (Calcium Sensing Receptor) is a Protein Coding gene. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant and Hyperparathyroidism, Neonatal. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase binding. An important paralog of this gene is GPRC6A.The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
    UniProt
    P41180
    途径
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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