CD44 抗体
Quick Overview for CD44 抗体 (ABIN2843760)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This CD44 monoclonal antibody is against human Peyer's patch endothelial cells (CD44) .
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亚型
- IgG2a kappa
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应用备注
- IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy." in: BMC complementary and alternative medicine, Vol. 16, pp. 113, (2016) (PubMed).
: "Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells." in: Stem cell reports, Vol. 1, Issue 6, pp. 575-89, (2015) (PubMed).
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All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy." in: BMC complementary and alternative medicine, Vol. 16, pp. 113, (2016) (PubMed).
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- CD44
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别名
- CD44
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背景
- The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
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分子量
- 81538
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基因ID
- 960
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NCBI登录号
- NP_000601, NP_001001389, NP_001001390, NP_001001391, NP_001001392, NP_001189484, NP_001189485, NP_001189486
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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