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CD44 抗体

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS, WB, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2843760
发货至: 中国

Quick Overview for CD44 抗体 (ABIN2843760)

抗原

See all CD44 抗体
CD44

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

Hermes-3
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This CD44 monoclonal antibody is against human Peyer's patch endothelial cells (CD44) .

    亚型

    IgG2a kappa
  • 应用备注

    IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Yan, Li, Xu, Chen, Wei, Fan, Chen, Li, Wang, Huang: "All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy." in: BMC complementary and alternative medicine, Vol. 16, pp. 113, (2016) (PubMed).

    Wu, Bluguermann, Kyupelyan, Latour, Gonzalez, Shah, Galic, Ge, Zhu, Petrigliano, Nsair, Miriuka, Li, Lyons, Crooks, McAllister, Van Handel, Adams, Evseenko: "Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells." in: Stem cell reports, Vol. 1, Issue 6, pp. 575-89, (2015) (PubMed).

  • 抗原

    CD44

    别名

    CD44

    背景

    The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

    分子量

    81538

    基因ID

    960

    NCBI登录号

    NP_000601, NP_001001389, NP_001001390, NP_001001391, NP_001001392, NP_001189484, NP_001189485, NP_001189486

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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