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AKT2 抗体

AKT2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 148CT5-4-1-4 unconjugated
产品编号 ABIN659024
发货至: 中国
  • 抗原 See all AKT2 抗体
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 158
    • 28
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    小鼠
    克隆类型
    • 159
    • 34
    单克隆
    标记
    • 97
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    This AKT2 antibody is un-conjugated
    应用范围
    • 163
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This AKT2 monoclonal antibody is generated from mouse immunized with AKT2 recombinant protein.
    克隆位点
    148CT5-4-1-4
    亚型
    IgG1
    Top Product
    Discover our top product AKT2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:500-1:2000. WB: 1:100~500. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Sun, Zhang, Wang, Jin, Jia, Yu, Chen: "MiRNA-615-5p functions as a tumor suppressor in pancreatic ductal adenocarcinoma by targeting AKT2." in: PLoS ONE, Vol. 10, Issue 4, pp. e0119783, (2015) (PubMed).

    Cui, Lin, Zuo, Zhang, Dong, Hu, Luo, Chen, Lu: "AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo." in: OncoTargets and therapy, Vol. 8, pp. 1681-90, (2015) (PubMed).

  • 抗原
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    别名
    AKT2 (AKT2 产品)
    别名
    AKT2 antibody, pkbb antibody, pkbbeta antibody, pkbss antibody, prkbb antibody, rac-beta antibody, v-akt2 antibody, 2410016A19Rik antibody, AW554154 antibody, PKB antibody, PKBbeta antibody, HIHGHH antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, cb945 antibody, akt2-a antibody, AKT serine/threonine kinase 2 antibody, v-akt murine thymoma viral oncogene homolog 2 antibody, thymoma viral proto-oncogene 2 antibody, v-akt murine thymoma viral oncogene homolog 2 L homeolog antibody, AKT2 antibody, akt2 antibody, Akt2 antibody, akt2.L antibody
    背景
    AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
    分子量
    55769
    基因ID
    208
    NCBI登录号
    NP_001617
    UniProt
    P31751
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
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