Neuregulin 2 抗体 (AA 361-410)
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Quick Overview for Neuregulin 2 抗体 (AA 361-410) (ABIN6579377)
抗原
See all Neuregulin 2 (NRG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 361-410
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原理
- Neuregulin-2 Antibody
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特异性
- Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human NRG2. AA range:361-410
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Neuregulin 2 (NRG2)
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别名
- NRG2
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背景
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Synonyms: NRG2, NTAK, Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2
Background: This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010],
Gene Name: NRG2
Protein Name: Pro-neuregulin-2 membrane-bound isoform
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分子量
- 91 kDa
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基因ID
- 9542
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UniProt
- O14511
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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