Metabotropic Glutamate Receptor 1 抗体 (C-Term)
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- 抗原 See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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抗原表位
- AA 1095-1123, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Metabotropic Glutamate Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This GRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1095-1123 amino acids from the C-terminal region of human GRM1.
- 克隆位点
- RB33631
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GRM1 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- GRM1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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- 抗原
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
- 别名
- GRM1 (GRM1 产品)
- 别名
- fj39d05 antibody, wu:fj39d05 antibody, si:ch211-51a19.1 antibody, Glura antibody, mGlutR antibody, GB18621 antibody, GPRC1A antibody, MGLU1 antibody, MGLUR1 antibody, SCAR13 antibody, 4930455H15Rik antibody, ENSMUSG00000075319 antibody, Gm10828 antibody, Gprc1a antibody, mGluR1 antibody, nmf373 antibody, rcw antibody, wobl antibody, glutamate metabotropic receptor 1 antibody, glutamate receptor, metabotropic 1a antibody, metabotropic glutamate receptor 1 antibody, glutamate receptor, metabotropic 1 antibody, GRM1 antibody, grm1a antibody, mGlutR1 antibody, Grm1 antibody
- 背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms, some of which may have distinct functions. [provided by RefSeq].
- 分子量
- 132357
- 基因ID
- 2911
- NCBI登录号
- NP_001264993, NP_001264994, NP_001264995, NP_001264996
- UniProt
- Q13255
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