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NLRC4 抗体 (N-Term)

NLRC4 适用: 人 WB 宿主: 兔 Polyclonal RB33296 unconjugated
产品编号 ABIN657230
发货至: 中国
  • 抗原 See all NLRC4 抗体
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    抗原表位
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-145, N-Term
    适用
    • 38
    • 15
    • 6
    • 2
    宿主
    • 27
    • 9
    • 2
    克隆类型
    • 28
    • 10
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRC4 antibody is un-conjugated
    应用范围
    • 27
    • 17
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NLRC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the N-terminal region of human NLRC4.
    克隆位点
    RB33296
    亚型
    Ig Fraction
    Top Product
    Discover our top product NLRC4 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    别名
    NLRC4 (NLRC4 产品)
    别名
    CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
    背景
    In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.
    分子量
    116159
    NCBI登录号
    NP_001186067, NP_001186068, NP_067032
    UniProt
    Q9NPP4
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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