This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-462 amino acids from the C-terminal region of human TFAP2B.
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq].