APITD1 抗体
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- 抗原 See all APITD1 抗体
- APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APITD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human APITD1
- 亚型
- IgG
- Top Product
- Discover our top product APITD1 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))
- 别名
- APITD1 (APITD1 产品)
- 别名
- CENP-S antibody, CENPS antibody, FAAP16 antibody, MHF1 antibody, 2610040C18Rik antibody, 2810407L01Rik antibody, cenps antibody, mhf1 antibody, APITD1 antibody, Apitd1 antibody, Mhf1 antibody, apitd1 antibody, zgc:194319 antibody, centromere protein S antibody, apoptosis-inducing, TAF9-like domain 1 antibody, centromere protein S L homeolog antibody, CENPS antibody, Cenps antibody, cenps.L antibody, APITD1 antibody, cenps antibody
- 背景
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Synonyms: APITD1,Apoptosis-inducing TAF9-like domain-containing protein 1,apoptosis-inducing, TAF9-like domain 1,CENP-S,CENPS,CENPS,Centromere protein S,FAAP16,FANCM-interacting histone fold protein 1,Fanconi anemia-associated polypeptide of 16 kDa,MGC32686,MHF 1
Background: This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.
- 分子量
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Observed_MW: 16kDa
Calculated_MW: 9kDa/15kDa/19kDa
- 基因ID
- 100526739
- UniProt
- Q8N2Z9
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