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- 抗原 See all FIP1L1 抗体
- FIP1L1 (FIP1 Like 1 (FIP1L1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FIP1L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human FIP1L1 (NP_001128409.1).
- 亚型
- IgG
- Top Product
- Discover our top product FIP1L1 Primary Antibody
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anti-FIP1 Like 1 (FIP1L1) antibody
FIP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 1-300) antibodyFIP1L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 1-378) antibodyFIP1L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-FIP1 Like 1 (FIP1L1) antibodyFIP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 509-558) antibodyFIP1L1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 斑马鱼, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (C-Term) antibodyFIP1L1 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 斑马鱼, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FIP1L1 (FIP1 Like 1 (FIP1L1))
- 别名
- FIP1L1 (FIP1L1 产品)
- 别名
- FIP1 antibody, Rhe antibody, hFip1 antibody, 1300019H17Rik antibody, Rje antibody, fip1l1 antibody, wu:fd36f11 antibody, zgc:103421 antibody, factor interacting with PAPOLA and CPSF1 antibody, factor interacting with PAPOLA and CPSF1 S homeolog antibody, FIP1 like 1 (S. cerevisiae) antibody, FIP1 like 1b (S. cerevisiae) antibody, fip1l1 antibody, FIP1L1 antibody, fip1l1.S antibody, Fip1l1 antibody, fip1l1b antibody
- 背景
- This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- 分子量
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Observed_MW: 75kDa
Calculated_MW: 40kDa/58kDa/65kDa/66kDa
- 基因ID
- 81608
- UniProt
- Q6UN15
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