IRAK4 抗体
Quick Overview for IRAK4 抗体 (ABIN6570285)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human IRAK4
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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别名
- IRAK4
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背景
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Synonyms: IL-1 receptor-associated kinase 4,Interleukin 1 receptor associated kinase 4 mutant form 1,Interleukin-1 receptor-associated kinase 4,Interleukin1 receptor associated kinase 4,IPD1,IRAK 4,IRAK-4,IRAK4,IRAK4 mutated form 1,IRAK4,LOC 51135,NY REN 64,NY REN 64 antigen,NY-REN-64,REN64,Renal carcinoma antigen NY-REN-64
Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 55kDa
Calculated_MW: 37kDa/51kDa
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基因ID
- 51135
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UniProt
- Q9NWZ3
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途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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