COMT 抗体
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- 抗原 See all COMT 抗体
- COMT (Catechol-O-Methyltransferase (COMT))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COMT antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human COMT (NP_009294.1).
- 亚型
- IgG
- Top Product
- Discover our top product COMT Primary Antibody
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- 应用备注
- IHC 1:50-1:200 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- COMT (Catechol-O-Methyltransferase (COMT))
- 别名
- COMT (COMT 产品)
- 别名
- Comt1 antibody, D16Wsu103e antibody, D330014B15Rik antibody, COMT antibody, mb-comt antibody, s-comt antibody, comt antibody, MGC154444 antibody, zgc:114157 antibody, si:dkey-13a21.15 antibody, zK13A21.15 antibody, zgc:162236 antibody, catechol-O-methyltransferase antibody, microRNA 4761 antibody, catechol-O-methyltransferase S homeolog antibody, methyltransferase antibody, catechol-o-methyltransferase antibody, catechol-O-methyltransferase a antibody, catechol-O-methyltransferase b antibody, catechol O-methyltransferase antibody, COMT antibody, Comt antibody, MIR4761 antibody, comt antibody, comt.2 antibody, comt.S antibody, Rv1703c antibody, Mb1729c antibody, comta antibody, comtb antibody, LOC100354142 antibody
- 背景
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
- 分子量
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Observed_MW: 28kDa, 32kDa
Calculated_MW: 24kDa/30kDa
- 基因ID
- 1312
- UniProt
- P21964
- 途径
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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