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AFT1 抗体

AFT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5962899
发货至: 中国
  • 抗原 See all AFT1 抗体
    AFT1 (Activating Transcription Factor 1 (AFT1))
    适用
    • 109
    • 46
    • 25
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 102
    • 7
    • 2
    • 1
    克隆类型
    • 99
    • 13
    多克隆
    标记
    • 59
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This AFT1 antibody is un-conjugated
    应用范围
    • 80
    • 37
    • 22
    • 15
    • 15
    • 14
    • 14
    • 10
    • 10
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ATF1
    亚型
    IgG
    Top Product
    Discover our top product AFT1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    AFT1 (Activating Transcription Factor 1 (AFT1))
    别名
    ATF1 (AFT1 产品)
    别名
    ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
    背景

    Synonyms: Activating transcription factor 1,ATF 1,atf1,ATF1 EWS fusion gene,ATF1 FUS fusion gene,ATF1,cAMP dependent transcription factor 1,cAMP-dependent transcription factor ATF-1,Cyclic AMP dependent transcription factor ATF 1,Cyclic AMP dependent transcription factor ATF1,Cyclic AMP-dependent transcription factor ATF-1,EWS AFT1,FUS ATF 1,FUS/ATF 1,Protein TREB36,RNA binding protein activating transcription factor 1 fusion protein,TREB 36,TREB36,TREB36 protein

    Background: This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

    分子量

    Observed_MW: 27-36kDa

    Calculated_MW: 15kDa/29kDa

    基因ID
    466
    UniProt
    P18846
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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