Bestrophin 1 抗体
-
- 抗原 See all Bestrophin 1 (BEST1) 抗体
- Bestrophin 1 (BEST1)
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Bestrophin 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human BEST1
- 亚型
- IgG
- Top Product
- Discover our top product BEST1 Primary Antibody
-
-
- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
-
- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- Bestrophin 1 (BEST1)
- 别名
- BEST1 (BEST1 产品)
- 别名
- CG6264 antibody, Dbest antibody, Dmel\\CG6264 antibody, anon-WO0118547.380 antibody, best antibody, dBest1 antibody, dbest1 antibody, dmBest1 antibody, BEST1 antibody, VMD2 antibody, best-1 antibody, ARB antibody, BEST antibody, BMD antibody, RP50 antibody, TU15B antibody, Bmd antibody, Vmd2 antibody, mBest1 antibody, Bestrophin 1 antibody, bestrophin 1 antibody, Best1 antibody, BEST1 antibody, best1 antibody, Bm1_25500 antibody
- 背景
-
Synonyms: ARB,BEST 1,BEST,Best disease,Best macular dystrophy,BEST1,BEST1,Best1V1Delta2,Bestrophin 1,Bestrophin-1,Bestrophin1,BMD,mBest1,RP50,TU15B,Vitelliform macular dystrophy 2,Vitelliform macular dystrophy,Vitelliform macular dystrophy protein 2,VMD 2,VMD2
Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
- 分子量
-
Observed_MW: 70kDa
Calculated_MW: 57kDa/67kDa/69kDa
- 基因ID
- 7439
- UniProt
- O76090
-