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FGD4 抗体 (N-Term)

FGD4 适用: 人 WB 宿主: 兔 Polyclonal RB32509 unconjugated
产品编号 ABIN656907
发货至: 中国
  • 抗原 See all FGD4 抗体
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    抗原表位
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    AA 157-186, N-Term
    适用
    • 23
    • 2
    • 2
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This FGD4 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This FGD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the N-terminal region of human FGD4.
    克隆位点
    RB32509
    亚型
    Ig Fraction
    Top Product
    Discover our top product FGD4 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    FGD4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    别名
    FGD4 (FGD4 产品)
    别名
    CMT4H antibody, FRABP antibody, ZFYVE6 antibody, 9030023J02Rik antibody, 9330209B17Rik antibody, Frabp antibody, FYVE, RhoGEF and PH domain containing 4 antibody, FGD4 antibody, Fgd4 antibody
    背景
    This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq].
    分子量
    86626
    基因ID
    121512
    NCBI登录号
    NP_640334
    UniProt
    Q96M96
    途径
    Neurotrophin Signaling Pathway
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