CYBB 抗体
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- 抗原 See all CYBB 抗体
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYBB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human CYBB
- 亚型
- IgG
- Top Product
- Discover our top product CYBB Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
- 别名
- CYBB (CYBB 产品)
- 背景
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Synonyms: AMCBX2,CGD,CGD91-phox,CY24B,CYBB,Cytochrome b 245,beta polypeptide,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,gp91-1,gp91-phox,GP91PHOX,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,NOX2,p22 phagocyte B-cytochrome,P91 PHOX,p91-PHOX,Superoxide-generating NADPH oxidase heavy chain subunit
Background: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
- 分子量
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Observed_MW: 65kDa
Calculated_MW: 65kDa
- 基因ID
- 1536
- UniProt
- P04839
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