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CYBB 抗体

CYBB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5964622
发货至: 中国
  • 抗原 See all CYBB 抗体
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    适用
    • 63
    • 42
    • 42
    • 19
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 6
    • 2
    克隆类型
    • 49
    • 14
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYBB antibody is un-conjugated
    应用范围
    • 41
    • 19
    • 18
    • 13
    • 13
    • 9
    • 9
    • 5
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human CYBB
    亚型
    IgG
    Top Product
    Discover our top product CYBB Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000 IHC 1:50 - 1:200
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    别名
    CYBB (CYBB 产品)
    背景

    Synonyms: AMCBX2,CGD,CGD91-phox,CY24B,CYBB,Cytochrome b 245,beta polypeptide,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,gp91-1,gp91-phox,GP91PHOX,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,NOX2,p22 phagocyte B-cytochrome,P91 PHOX,p91-PHOX,Superoxide-generating NADPH oxidase heavy chain subunit

    Background: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

    分子量

    Observed_MW: 65kDa

    Calculated_MW: 65kDa

    基因ID
    1536
    UniProt
    P04839
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