RIN2 抗体
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- 抗原 See all RIN2 抗体
- RIN2 (Ras and Rab Interactor 2 (RIN2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human RIN2
- 亚型
- IgG
- Top Product
- Discover our top product RIN2 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- RIN2 (Ras and Rab Interactor 2 (RIN2))
- 别名
- RIN2 (RIN2 产品)
- 别名
- RIN2 antibody, RINL antibody, rassf4 antibody, MACS antibody, RASSF4 antibody, 2010003K16Rik antibody, 4632403N06Rik antibody, AW821980 antibody, Ras and Rab interactor 2 antibody, Rin2 antibody, RIN2 antibody, rin2 antibody
- 背景
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Synonyms: MACS ,RAB5 interacting protein 2,Ras and Rab interactor 2,RAS association (RalGDS/AF-6) domain containing protein JC265,Ras association domain family 4,Ras inhibitor JC265,Ras interaction/interference protein 2,RASSF4,RIN 2,RIN2,RIN2
Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 120kDa
Calculated_MW: 100kDa/105kDa
- 基因ID
- 54453
- UniProt
- Q8WYP3
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